Cats

Chlorambucil and its use in both IBD and Lymphosarcoma

Chlorambucil is an alkylating antineoplastic medication that is used to treat many immune response disease states in animals. This medication can be very useful in treating both irritable bowel syndrome (IBD) and certain cancers like lymphosarcoma. Both conditions will present with similar clinical symptoms but a biopsy will confirm the suspicion of cancer. Investigators have [...]

USP 800 and How It Relates to Your Veterinary Practice

What is USP 800?  USP 800 has many healthcare professionals on edge as to how it relates to their field and practice scope. This federal standard was implemented with the intention of protecting the environment as well as any and all health care personnel that are exposed to hazardous drugs in the workspace. With the [...]

Enrofloxacin- Uses and Forms for Ear Infections

Enrofloxacin: This is in the drug class fluoroquinolones and is a broad-spectrum bactericidal antibiotic.  It can be administered to both cats and dogs to treat ear infections. Enrofloxacin is effective against both gram positive and gram negative bacteria, particularly E.coli, Pseudomonas aeruginosa, Vibri, Staphylococci and Brucella. Enrofloxacin is a beneficial choice for difficult to treat [...]

Piroxicam – Uses and Forms for Arthritis

PIROXICAM: This is in the drug class of Non-Steroidal Anti-Inflammatory Drugs (NSAIDís) used to treat arthritis. Piroxicam can be given to both cats and dogs to relieve pain, inflammation and to a lesser degree high temperature. NSAIDís action is to block cyclooxygenase enzymes 1 and 2, which lower prostaglandin levels that are higher in times [...]

Management of Feline Hyperthyroidism with Methimazole

Hyperthyroidism is the most common endocrine disorder in felines, with a disease prevalence of approximately 0.33%.The pathophysiology of feline hyperthyroidism is most commonly due to a benign hyperplasia of the thyd gland that leads to an increased production of T3 and T4 in the affected animal. This adenomatous hyperplasia is responsible for 98% of cases [...]

Tramadol: An Appropriate Analgesic?

Uses/Indications: Tramadol is a synthetic codeine analogue and a weak μ opioid receptor agonist. Tramadol also inhibits neuronal reuptake of norepinephrine and serotonin and may facilitate serotonin release. Therefore, it is recommended for acute and chronic pain and may be used alone to treat mild pain or adjunctively in a multimodal plan to treat moderate [...]

Amantadine for Chronic Pain

Uses/Indications: Amantadine may have efficacy and clinical usefulness against some veterinary viral diseases, but presently the greatest interest for its use in small animals is as an NMDA antagonist in the adjunctive treatment of chronic pain, particularly those tolerant to opioids. Amantadine antagonizes the N-methyl-D-aspartate (NMDA) receptor, and chronic pain can be maintained or exacerbated [...]

Tramadol: An Appropriate Analgesic?

Uses/Indications: Tramadol is a synthetic codeine analogue and a weak μ opioid receptor agonist. Tramadol also inhibits neuronal reuptake of norepinephrine and serotonin and may facilitate serotonin release. Therefore, it is recommended for acute and chronic pain and may be used alone to treat mild pain or adjunctively in a multimodal plan to treat moderate [...]

Mirtazapine for Appetite Stimulation in Dogs and Cats

Uses/Indications:  Treatment of chemotherapy induced nausea and vomiting (CINV), anorexia, associated with renal failure (azotemia), congestive heart failure, gastrointestinal disorders, liver disease, or neoplasia. Studies/Case Reports: For years, veterinarians have used B-vitamins and steroids for appetite stimulation in canines and benzodiazepines in felines. Pharmacy faculty at The Mississippi State College of Veterinary Medicine used mirtazapine [...]

Veterinary Amitriptyline

Amitriptyline is one of the most widely used tricyclic antidepressants (TCAs) in companion animal behavioral medicine, exerting antihistaminic, anti-inflammatory, analgesic, and antidepressant effects. It increases synaptic activity of serotonin and norepinephrine, has significant central and peripheral anticholinergic activity, and stimulates β-adrenergic receptors in smooth muscle (e.g. the bladder), causing a decrease in smooth muscle excitability [...]