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Heart Failure Treatment With Pimobendan

Optimizing Canine Heart Failure Treatment with Pimobendan

Heart disease is a common ailment in dogs, and managing congestive heart failure (CHF) requires a multi-faceted approach. Pimobendan, a widely-used drug, has revolutionized CHF management in canines. This product is used to help improve the ability of the heart to pump blood. However, compounded pimobendane presents a unique opportunity to enhance treatment protocols and improve patient outcomes.

The practice of compounding pimobendan allows veterinarians to create personalized formulations, maximizing the drug’s efficacy while minimizing adverse effects. By adjusting dosages and combinations, compounded pimobendane can be a potent tool in treating complex cardiac cases, such as concurrent conditions of adverse reactions to standard medications. In 2009, the American College of Veterinary Internal Medicine included pimobendane in their consensus statement regarding the treatment of chronic valvular heart disease.

Compounded pimobendan enables precise dosage adjustments, optimizing its impact on cardiac function without compromising safety. Tailored formulations can result in more palatable medications, ensuring great pet owner compliance with treatment plans. Combining pimobendan within other drugs allows for targeted therapy, addressing individual patient needs and optimizing response. This can greatly alleviate pill/volume burden since many CHF patients cannot get their disease state controlled with one single medication.

Dosing in Canines

0.4-0.6mg/kg/day in divided doses


Klein, S., Nolte, I., Rumstedt, K. et al. (2021). The effect of treatment with pimobendan in dogs with preclinical mitral valve disease – a placebo-controlled double-blinded crossover study. BMC Vet Res 17, 310.

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