Piroxicam is in the drug class of Non-Steroidal Anti-Inflammatory Drugs (NSAID’s) used to treat arthritis. This can be given to both cats and dogs to relieve pain, inflammation and to a lesser degree elevated temperature whereas its mechanism against cancer cells is unknown. NSAID’s action is to block cyclooxygenase (COX) enzymes 1 and 2, which lower prostaglandin levels that are higher in times of inflammation. The thought is inhibiting COX enzyme reduces inflammation caused by tumor cells and blood vessel growth of tumor cells.

Proper hydration is an important consideration since piroxicam can have problems with the kidneys and stomach. Due to this, extended use may necessitate monitoring for ulcers, gastrointestinal bleeding, and kidney function. Other considerations include caution in animals with decreased heart function. It is recommended to give Piroxicam with food to minimize gastrointestinal side effects.

This medication could be found in strengths available for human use. Fortunately, Pharmacy Solutions has many unique flavors specifically for animals such as chicken, beef, and fish. Compounded formulations for Piroxicam include liquid or capsules to tailored doses specifically for your animal’s weight.

Dog and Feline Dosing: 0.3mg/kg by mouth once daily with food